2cej

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Current revision (14:15, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2cej' size='340' side='right'caption='[[2cej]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2cej' size='340' side='right'caption='[[2cej]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cej]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CEJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CEJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cej]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CEJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CEJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AH:3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE'>1AH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1wbk|1wbk]], [[1wbm|1wbm]], [[2cem|2cem]], [[2cen|2cen]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AH:3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE'>1AH</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cej OCA], [https://pdbe.org/2cej PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cej RCSB], [https://www.ebi.ac.uk/pdbsum/2cej PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cej ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cej OCA], [https://pdbe.org/2cej PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cej RCSB], [https://www.ebi.ac.uk/pdbsum/2cej PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cej ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8Q3H0_9HIV1 Q8Q3H0_9HIV1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: HIV-1 retropepsin]]
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[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ekegren, J K]]
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[[Category: Ekegren JK]]
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[[Category: Ginman, N]]
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[[Category: Ginman N]]
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[[Category: Hallberg, A]]
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[[Category: Hallberg A]]
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[[Category: Johansson, A]]
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[[Category: Johansson A]]
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[[Category: Larhed, M]]
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[[Category: Larhed M]]
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[[Category: Samuelsson, B]]
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[[Category: Samuelsson B]]
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[[Category: Unge, T]]
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[[Category: Unge T]]
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[[Category: Wallberg, H]]
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[[Category: Wallberg H]]
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[[Category: Aspartyl protease]]
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[[Category: Hiv-1]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Protease]]
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Current revision

P1' Extended HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-State Mimicking Scaffold

PDB ID 2cej

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