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2cfi

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Current revision (14:15, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2cfi' size='340' side='right'caption='[[2cfi]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='2cfi' size='340' side='right'caption='[[2cfi]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cfi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CFI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cfi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CFI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZZZ:6-FORMYLTETRAHYDROPTERIN'>ZZZ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bw0|2bw0]], [[2cq8|2cq8]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZZZ:6-FORMYLTETRAHYDROPTERIN'>ZZZ</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfi OCA], [https://pdbe.org/2cfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cfi RCSB], [https://www.ebi.ac.uk/pdbsum/2cfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfi OCA], [https://pdbe.org/2cfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cfi RCSB], [https://www.ebi.ac.uk/pdbsum/2cfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfi ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AL1L1_HUMAN AL1L1_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Formyltetrahydrofolate dehydrogenase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C]]
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[[Category: Arrowsmith C]]
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[[Category: Edwards, A]]
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[[Category: Edwards A]]
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[[Category: Ehn, M]]
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[[Category: Ehn M]]
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[[Category: Graslund, S]]
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[[Category: Graslund S]]
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[[Category: Hallberg, M]]
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[[Category: Hallberg M]]
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[[Category: Hammarstrom, M]]
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[[Category: Hammarstrom M]]
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[[Category: Kotenyova, T]]
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[[Category: Kotenyova T]]
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[[Category: Kursula, P]]
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[[Category: Kursula P]]
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[[Category: Nilsson-Ehle, P]]
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[[Category: Nilsson-Ehle P]]
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[[Category: Nordlund, P]]
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[[Category: Nordlund P]]
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[[Category: Ogg, D J]]
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[[Category: Ogg DJ]]
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[[Category: Persson, C]]
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[[Category: Persson C]]
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[[Category: Sagemark, J]]
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[[Category: Sagemark J]]
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[[Category: Schuler, H]]
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[[Category: Schuler H]]
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[[Category: Stenmark, P]]
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[[Category: Stenmark P]]
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[[Category: Sundstrom, M]]
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[[Category: Sundstrom M]]
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[[Category: Thorsell, A]]
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[[Category: Thorsell A]]
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[[Category: Weigelt, J]]
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[[Category: Weigelt J]]
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[[Category: Folate binding]]
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[[Category: Nadp]]
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[[Category: One-carbon metabolism]]
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[[Category: Oxidoreductase]]
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[[Category: Phosphopantetheine]]
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[[Category: Tetrahydrofolate]]
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Current revision

The hydrolase domain of human 10-FTHFD in complex with 6- formyltetrahydropterin

PDB ID 2cfi

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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