This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2chl
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2chl' size='340' side='right'caption='[[2chl]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='2chl' size='340' side='right'caption='[[2chl]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2chl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2chl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHL FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DKI:5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE'>DKI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DKI:5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE'>DKI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chl OCA], [https://pdbe.org/2chl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chl RCSB], [https://www.ebi.ac.uk/pdbsum/2chl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chl ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chl OCA], [https://pdbe.org/2chl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chl RCSB], [https://www.ebi.ac.uk/pdbsum/2chl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/KC1G3_HUMAN KC1G3_HUMAN] Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 24: | Line 25: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith C]] |
| - | [[Category: Bunkoczi | + | [[Category: Bunkoczi G]] |
| - | [[Category: Das | + | [[Category: Das S]] |
| - | + | [[Category: Edwards A]] | |
| - | [[Category: Edwards | + | [[Category: Fedorov O]] |
| - | [[Category: Fedorov | + | [[Category: Gileadi O]] |
| - | [[Category: Gileadi | + | [[Category: Knapp S]] |
| - | [[Category: Knapp | + | [[Category: Rellos P]] |
| - | [[Category: Rellos | + | [[Category: Salah E]] |
| - | [[Category: Salah | + | [[Category: Savitsky P]] |
| - | [[Category: Savitsky | + | [[Category: Sundstrom M]] |
| - | [[Category: Sundstrom | + | [[Category: Ugochukwu E]] |
| - | [[Category: Ugochukwu | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structure of casein kinase 1 gamma 3
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith C | Bunkoczi G | Das S | Edwards A | Fedorov O | Gileadi O | Knapp S | Rellos P | Salah E | Savitsky P | Sundstrom M | Ugochukwu E | Weigelt J | Von Delft F
