2cio
From Proteopedia
(Difference between revisions)
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<StructureSection load='2cio' size='340' side='right'caption='[[2cio]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='2cio' size='340' side='right'caption='[[2cio]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2cio]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Carica_papaya Carica papaya] and [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2cio]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Carica_papaya Carica papaya] and [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CIO FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr> |
| - | + | ||
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cio OCA], [https://pdbe.org/2cio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cio RCSB], [https://www.ebi.ac.uk/pdbsum/2cio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cio ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cio OCA], [https://pdbe.org/2cio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cio RCSB], [https://www.ebi.ac.uk/pdbsum/2cio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cio ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q868H0_9TRYP Q868H0_9TRYP] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Carica papaya]] | [[Category: Carica papaya]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Papain]] | ||
| - | [[Category: Alphey, M S]] | ||
| - | [[Category: Hunter, W N]] | ||
| - | [[Category: Allergen]] | ||
| - | [[Category: Complex hydrolase-inhibitor]] | ||
| - | [[Category: Cysteine protease]] | ||
| - | [[Category: Hydrolase]] | ||
| - | [[Category: Hydrolase-inhibitor complex]] | ||
| - | [[Category: Hydrolase/inhibitor]] | ||
| - | [[Category: Icp]] | ||
| - | [[Category: Inhibitor]] | ||
| - | [[Category: Protease]] | ||
| - | [[Category: Thiol protease]] | ||
[[Category: Trypanosoma brucei]] | [[Category: Trypanosoma brucei]] | ||
| - | [[Category: | + | [[Category: Alphey MS]] |
| + | [[Category: Hunter WN]] | ||
Current revision
The high resolution x-ray structure of papain complexed with fragments of the Trypanosoma brucei cysteine protease inhibitor ICP.
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