2iyx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:30, 13 December 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2iyx' size='340' side='right'caption='[[2iyx]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
<StructureSection load='2iyx' size='340' side='right'caption='[[2iyx]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2iyx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IYX FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2iyx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IYX FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1l4u|1l4u]], [[1l4y|1l4y]], [[1u8a|1u8a]], [[1zyu|1zyu]], [[2g1j|2g1j]], [[2g1k|2g1k]], [[2iyq|2iyq]], [[2iyr|2iyr]], [[2iys|2iys]], [[2iyt|2iyt]], [[2iyu|2iyu]], [[2iyv|2iyv]], [[2iyw|2iyw]], [[2iyy|2iyy]], [[2iyz|2iyz]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Shikimate_kinase Shikimate kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.71 2.7.1.71] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyx OCA], [https://pdbe.org/2iyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iyx RCSB], [https://www.ebi.ac.uk/pdbsum/2iyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iyx OCA], [https://pdbe.org/2iyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iyx RCSB], [https://www.ebi.ac.uk/pdbsum/2iyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iyx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/AROK_MYCTU AROK_MYCTU]] Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<ref>PMID:11483005</ref> <ref>PMID:17020768</ref>
+
[https://www.uniprot.org/uniprot/AROK_MYCTU AROK_MYCTU] Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<ref>PMID:11483005</ref> <ref>PMID:17020768</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 32: Line 31:
==See Also==
==See Also==
-
*[[Shikimate kinase|Shikimate kinase]]
+
*[[Shikimate kinase 3D structures|Shikimate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 38: Line 37:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Myctu]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Shikimate kinase]]
+
[[Category: Bartunik HD]]
-
[[Category: Bartunik, H D]]
+
[[Category: Bourenkov GP]]
-
[[Category: Bourenkov, G P]]
+
[[Category: Hartmann MD]]
-
[[Category: Hartmann, M D]]
+
[[Category: Oberschall A]]
-
[[Category: Oberschall, A]]
+
[[Category: Strizhov N]]
-
[[Category: Strizhov, N]]
+
-
[[Category: Amino-acid biosynthesis]]
+
-
[[Category: Aromatic amino acid biosynthesis]]
+
-
[[Category: Atp-binding]]
+
-
[[Category: Kinase]]
+
-
[[Category: Magnesium]]
+
-
[[Category: Metal- binding]]
+
-
[[Category: Nucleotide- binding]]
+
-
[[Category: P-loop kinase]]
+
-
[[Category: Shikimate pathway]]
+
-
[[Category: Transferase]]
+

Current revision

Shikimate kinase from Mycobacterium tuberculosis in complex with shikimate and SO4

PDB ID 2iyx

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2iyx"
Personal tools