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| | <StructureSection load='2uxv' size='340' side='right'caption='[[2uxv]], [[Resolution|resolution]] 2.61Å' scene=''> | | <StructureSection load='2uxv' size='340' side='right'caption='[[2uxv]], [[Resolution|resolution]] 2.61Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[2uxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UXV FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2uxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UXV FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2uxt|2uxt]]</div></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61Å</td></tr> |
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxv OCA], [https://pdbe.org/2uxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uxv RCSB], [https://www.ebi.ac.uk/pdbsum/2uxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxv ProSAT]</span></td></tr> | | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxv OCA], [https://pdbe.org/2uxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uxv RCSB], [https://www.ebi.ac.uk/pdbsum/2uxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxv ProSAT]</span></td></tr> |
| | </table> | | </table> |
| | == Function == | | == Function == |
| - | [[https://www.uniprot.org/uniprot/FTSP_ECOLI FTSP_ECOLI]] Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.[HAMAP-Rule:MF_00915]<ref>PMID:17766410</ref>
| + | [https://www.uniprot.org/uniprot/FTSP_ECOLI FTSP_ECOLI] Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.[HAMAP-Rule:MF_00915]<ref>PMID:17766410</ref> |
| | == Evolutionary Conservation == | | == Evolutionary Conservation == |
| | [[Image:Consurf_key_small.gif|200px|right]] | | [[Image:Consurf_key_small.gif|200px|right]] |
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| | __TOC__ | | __TOC__ |
| | </StructureSection> | | </StructureSection> |
| - | [[Category: Bacillus coli migula 1895]] | + | [[Category: Escherichia coli]] |
| | [[Category: Large Structures]] | | [[Category: Large Structures]] |
| - | [[Category: Berks, B C]] | + | [[Category: Berks BC]] |
| - | [[Category: Lea, S M]] | + | [[Category: Lea SM]] |
| - | [[Category: Roversi, P]] | + | [[Category: Roversi P]] |
| - | [[Category: Sargent, F]] | + | [[Category: Sargent F]] |
| - | [[Category: Tarry, M J]] | + | [[Category: Tarry MJ]] |
| - | [[Category: Cupredoxin-like]]
| + | |
| - | [[Category: Fts mutant suppressor]]
| + | |
| - | [[Category: Oxidoreductase]]
| + | |
| - | [[Category: Periplasmic]]
| + | |
| - | [[Category: Sufi]]
| + | |
| Structural highlights
Function
FTSP_ECOLI Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.[HAMAP-Rule:MF_00915][1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The Escherichia coli protein SufI (FtsP) has recently been proposed to be a component of the cell division apparatus. The SufI protein is also in widespread experimental use as a model substrate in studies of the Tat (twin arginine translocation) protein transport system. We have used SufI-GFP (green fluorescent protein) fusions to show that SufI localizes to the septal ring in the dividing cell. We have also determined the structure of SufI by X-ray crystallography to a resolution of 1.9 A. SufI is structurally related to the multicopper oxidase superfamily but lacks metal cofactors. The structure of SufI suggests it serves a scaffolding rather than an enzymatic role in the septal ring and reveals regions of the protein likely to be involved in the protein-protein interactions required to assemble SufI at the septal ring.
The Escherichia coli Cell Division Protein and Model Tat Substrate SufI (FtsP) Localizes to the Septal Ring and Has a Multicopper Oxidase-Like Structure.,Tarry M, Arends SJ, Roversi P, Piette E, Sargent F, Berks BC, Weiss DS, Lea SM J Mol Biol. 2008 Dec 25. PMID:19135451[2]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Samaluru H, SaiSree L, Reddy M. Role of SufI (FtsP) in cell division of Escherichia coli: evidence for its involvement in stabilizing the assembly of the divisome. J Bacteriol. 2007 Nov;189(22):8044-52. Epub 2007 Aug 31. PMID:17766410 doi:http://dx.doi.org/10.1128/JB.00773-07
- ↑ Tarry M, Arends SJ, Roversi P, Piette E, Sargent F, Berks BC, Weiss DS, Lea SM. The Escherichia coli Cell Division Protein and Model Tat Substrate SufI (FtsP) Localizes to the Septal Ring and Has a Multicopper Oxidase-Like Structure. J Mol Biol. 2008 Dec 25. PMID:19135451 doi:S0022-2836(08)01564-7
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