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2v00

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Current revision (14:59, 13 December 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2v00]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V00 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2v00]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V00 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=V15:2-AMINO-6-(2-PHENYLETHYL)PYRIMIDIN-4(3H)-ONE'>V15</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1e5o|1e5o]], [[1e80|1e80]], [[1e81|1e81]], [[1e82|1e82]], [[1eed|1eed]], [[1ent|1ent]], [[1gkt|1gkt]], [[1gvt|1gvt]], [[1gvu|1gvu]], [[1gvv|1gvv]], [[1gvw|1gvw]], [[1gvx|1gvx]], [[1od1|1od1]], [[1oew|1oew]], [[1oex|1oex]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=V15:2-AMINO-6-(2-PHENYLETHYL)PYRIMIDIN-4(3H)-ONE'>V15</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v00 OCA], [https://pdbe.org/2v00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v00 RCSB], [https://www.ebi.ac.uk/pdbsum/2v00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v00 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v00 OCA], [https://pdbe.org/2v00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v00 RCSB], [https://www.ebi.ac.uk/pdbsum/2v00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v00 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Cryphonectria parasitica]]
[[Category: Cryphonectria parasitica]]
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[[Category: Endothiapepsin]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Albert, J S]]
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[[Category: Albert JS]]
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[[Category: Beer, T De]]
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[[Category: De Beer T]]
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[[Category: Deinum, J]]
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[[Category: Deinum J]]
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[[Category: Edwards, P D]]
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[[Category: Edwards PD]]
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[[Category: Folmer, R H.A]]
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[[Category: Folmer RHA]]
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[[Category: Geschwindner, S]]
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[[Category: Geschwindner S]]
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[[Category: Olsson, L L]]
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[[Category: Olsson LL]]
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[[Category: Alzheimer's disease]]
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[[Category: Aspartyl protease]]
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[[Category: B- secretase]]
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[[Category: Bace]]
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[[Category: Fragment hit]]
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[[Category: Fragment-based lead generation]]
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[[Category: Hydrolase]]
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[[Category: Isocytosine]]
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[[Category: Protease]]
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[[Category: Surrogate protein]]
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[[Category: Zymogen]]
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Current revision

X-ray crystal structure of endothiapepsin complexed with compound 1

PDB ID 2v00

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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