2v9z

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Current revision (15:11, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2v9z' size='340' side='right'caption='[[2v9z]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='2v9z' size='340' side='right'caption='[[2v9z]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2v9z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_mycoides_roseum"_grotenfelt_1889 "bacterium mycoides roseum" grotenfelt 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2v9z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9Z FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9z OCA], [https://pdbe.org/2v9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9z RCSB], [https://www.ebi.ac.uk/pdbsum/2v9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9z ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9z OCA], [https://pdbe.org/2v9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9z RCSB], [https://www.ebi.ac.uk/pdbsum/2v9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
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[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacterium mycoides roseum grotenfelt 1889]]
 
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[[Category: Haloalkane dehalogenase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chovancova, E]]
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[[Category: Rhodococcus rhodochrous]]
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[[Category: Damborsky, J]]
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[[Category: Chovancova E]]
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[[Category: Emmer, J]]
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[[Category: Damborsky J]]
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[[Category: Jesenska, A]]
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[[Category: Emmer J]]
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[[Category: Koudelakova, T]]
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[[Category: Jesenska A]]
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[[Category: Lapkouski, M]]
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[[Category: Koudelakova T]]
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[[Category: Monincova, M]]
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[[Category: Kuta Smatanova I]]
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[[Category: Nagata, Y]]
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[[Category: Lapkouski M]]
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[[Category: Prokop, Z]]
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[[Category: Monincova M]]
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[[Category: Sato, Y]]
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[[Category: Nagata Y]]
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[[Category: Senda, T]]
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[[Category: Prokop Z]]
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[[Category: Smatanova, I Kuta]]
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[[Category: Sato Y]]
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[[Category: Detoxification]]
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[[Category: Senda T]]
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[[Category: Hydrolase]]
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[[Category: Plasmid]]
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Current revision

Structure of the Rhodococcus haloalkane dehalogenase mutant with enhanced enantioselectivity

PDB ID 2v9z

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