1oyp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1oyp.gif|left|200px]]
[[Image:1oyp.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1oyp |SIZE=350|CAPTION= <scene name='initialview01'>1oyp</scene>, resolution 2.76&Aring;
+
The line below this paragraph, containing "STRUCTURE_1oyp", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_nucleotidyltransferase tRNA nucleotidyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.56 2.7.7.56] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1oyp| PDB=1oyp | SCENE= }}
-
|RELATEDENTRY=[[1oyr|1OYR]], [[1oys|1OYS]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oyp OCA], [http://www.ebi.ac.uk/pdbsum/1oyp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1oyp RCSB]</span>
+
-
}}
+
'''Crystal Structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis'''
'''Crystal Structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis'''
Line 25: Line 22:
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Single protein]]
-
[[Category: tRNA nucleotidyltransferase]]
+
[[Category: TRNA nucleotidyltransferase]]
[[Category: Harlow, L S.]]
[[Category: Harlow, L S.]]
[[Category: Jensen, K F.]]
[[Category: Jensen, K F.]]
[[Category: Kadziola, A.]]
[[Category: Kadziola, A.]]
[[Category: Larsen, S.]]
[[Category: Larsen, S.]]
-
[[Category: transferase]]
+
[[Category: Transferase]]
-
[[Category: trna processing]]
+
[[Category: Trna processing]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:26:29 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:52:20 2008''
+

Revision as of 01:26, 3 May 2008

Image:1oyp.gif

Template:STRUCTURE 1oyp

Crystal Structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis


Overview

RNase PH is a member of the family of phosphorolytic 3' --> 5' exoribonucleases that also includes polynucleotide phosphorylase (PNPase). RNase PH is involved in the maturation of tRNA precursors and especially important for removal of nucleotide residues near the CCA acceptor end of the mature tRNAs. Wild-type and triple mutant R68Q-R73Q-R76Q RNase PH from Bacillus subtilis have been crystallized and the structures determined by X-ray diffraction to medium resolution. Wild-type and triple mutant RNase PH crystallize as a hexamer and dimer, respectively. The structures contain a rare left-handed beta alpha beta-motif in the N-terminal portion of the protein. This motif has also been identified in other enzymes involved in RNA metabolism. The RNase PH structure and active site can, despite low sequence similarity, be overlayed with the N-terminal core of the structure and active site of Streptomyces antibioticus PNPase. The surface of the RNase PH dimer fit the shape of a tRNA molecule.

About this Structure

1OYP is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Crystal structure of the phosphorolytic exoribonuclease RNase PH from Bacillus subtilis and implications for its quaternary structure and tRNA binding., Harlow LS, Kadziola A, Jensen KF, Larsen S, Protein Sci. 2004 Mar;13(3):668-77. Epub 2004 Feb 6. PMID:14767080 Page seeded by OCA on Sat May 3 04:26:29 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1oyp"
Personal tools