2vsv
From Proteopedia
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<StructureSection load='2vsv' size='340' side='right'caption='[[2vsv]], [[Resolution|resolution]] 1.82Å' scene=''> | <StructureSection load='2vsv' size='340' side='right'caption='[[2vsv]], [[Resolution|resolution]] 1.82Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2vsv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2vsv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VSV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VSV FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vsv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsv OCA], [https://pdbe.org/2vsv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vsv RCSB], [https://www.ebi.ac.uk/pdbsum/2vsv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsv ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vsv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vsv OCA], [https://pdbe.org/2vsv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vsv RCSB], [https://www.ebi.ac.uk/pdbsum/2vsv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vsv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RHPN2_HUMAN RHPN2_HUMAN] Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.<ref>PMID:12221077</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vsv ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vsv ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Burgess-Brown | + | [[Category: Burgess-Brown N]] |
| - | + | [[Category: Edwards A]] | |
| - | [[Category: Edwards | + | [[Category: Elkins J]] |
| - | [[Category: Elkins | + | [[Category: Kochan G]] |
| - | [[Category: Kochan | + | [[Category: Murray JW]] |
| - | [[Category: Murray | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Pike ACW]] |
| - | [[Category: Pike | + | [[Category: Pilka ES]] |
| - | [[Category: Pilka | + | [[Category: Roos A]] |
| - | [[Category: Roos | + | [[Category: Shafqat N]] |
| - | [[Category: Shafqat | + | [[Category: Sun Z]] |
| - | [[Category: Sun | + | [[Category: Wikstrom M]] |
| - | [[Category: Wikstrom | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
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Current revision
Crystal structure of the PDZ domain of human rhophilin-2
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Burgess-Brown N | Edwards A | Elkins J | Kochan G | Murray JW | Oppermann U | Pike ACW | Pilka ES | Roos A | Shafqat N | Sun Z | Wikstrom M | Von Delft F
