2wjz
From Proteopedia
(Difference between revisions)
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<StructureSection load='2wjz' size='340' side='right'caption='[[2wjz]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2wjz' size='340' side='right'caption='[[2wjz]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2wjz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2wjz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJZ FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.601Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjz OCA], [https://pdbe.org/2wjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjz RCSB], [https://www.ebi.ac.uk/pdbsum/2wjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjz ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjz OCA], [https://pdbe.org/2wjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjz RCSB], [https://www.ebi.ac.uk/pdbsum/2wjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
- | + | [https://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013] | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
- | *[[ | + | *[[IGPS 3D structures|IGPS 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: Atcc 43589]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Babinger | + | [[Category: Thermotoga maritima]] |
- | [[Category: Haeger | + | [[Category: Babinger K]] |
- | [[Category: Kuper | + | [[Category: Haeger MC]] |
- | [[Category: List | + | [[Category: Kuper J]] |
- | [[Category: Razeto | + | [[Category: List F]] |
- | [[Category: Sterner | + | [[Category: Razeto A]] |
- | [[Category: Vega | + | [[Category: Sterner R]] |
- | [[Category: Wilmanns | + | [[Category: Vega MC]] |
- | + | [[Category: Wilmanns M]] | |
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Current revision
Crystal structure of (HisH) K181A Y138A mutant of imidazoleglycerolphosphate synthase (HisH HisF) which displays constitutive glutaminase activity
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Categories: Large Structures | Thermotoga maritima | Babinger K | Haeger MC | Kuper J | List F | Razeto A | Sterner R | Vega MC | Wilmanns M