2do5
From Proteopedia
(Difference between revisions)
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==Solution structure of the SAP domain of human splicing factor 3B subunit 2== | ==Solution structure of the SAP domain of human splicing factor 3B subunit 2== | ||
- | <StructureSection load='2do5' size='340' side='right'caption='[[2do5 | + | <StructureSection load='2do5' size='340' side='right'caption='[[2do5]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2do5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2do5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DO5 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2do5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2do5 OCA], [https://pdbe.org/2do5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2do5 RCSB], [https://www.ebi.ac.uk/pdbsum/2do5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2do5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2do5 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2do5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2do5 OCA], [https://pdbe.org/2do5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2do5 RCSB], [https://www.ebi.ac.uk/pdbsum/2do5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2do5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2do5 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
- | + | [https://www.uniprot.org/uniprot/SF3B2_HUMAN SF3B2_HUMAN] Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron. | |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Inoue | + | [[Category: Inoue M]] |
- | [[Category: Kigawa | + | [[Category: Kigawa T]] |
- | [[Category: Muto | + | [[Category: Muto Y]] |
- | + | [[Category: Shirouzu M]] | |
- | [[Category: Shirouzu | + | [[Category: Suzuki S]] |
- | [[Category: Suzuki | + | [[Category: Terada T]] |
- | [[Category: Terada | + | [[Category: Yokoyama S]] |
- | [[Category: Yokoyama | + | |
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Current revision
Solution structure of the SAP domain of human splicing factor 3B subunit 2
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Categories: Homo sapiens | Large Structures | Inoue M | Kigawa T | Muto Y | Shirouzu M | Suzuki S | Terada T | Yokoyama S