2elw

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Current revision (16:35, 13 December 2023) (edit) (undo)
 
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==Solution structure of the 5th C2H2 zinc finger of mouse Zinc finger protein 406==
==Solution structure of the 5th C2H2 zinc finger of mouse Zinc finger protein 406==
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<StructureSection load='2elw' size='340' side='right'caption='[[2elw]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2elw' size='340' side='right'caption='[[2elw]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2elw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2elw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ELW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Zfat1, Zfp406, Znf406 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2elw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elw OCA], [https://pdbe.org/2elw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2elw RCSB], [https://www.ebi.ac.uk/pdbsum/2elw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2elw ProSAT], [https://www.topsan.org/Proteins/RSGI/2elw TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2elw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2elw OCA], [https://pdbe.org/2elw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2elw RCSB], [https://www.ebi.ac.uk/pdbsum/2elw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2elw ProSAT], [https://www.topsan.org/Proteins/RSGI/2elw TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ZFAT_MOUSE ZFAT_MOUSE]] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated.<ref>PMID:18329245</ref>
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[https://www.uniprot.org/uniprot/ZFAT_MOUSE ZFAT_MOUSE] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated.<ref>PMID:18329245</ref>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Harada, T]]
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[[Category: Harada T]]
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[[Category: Kigawa, T]]
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[[Category: Kigawa T]]
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[[Category: Koshiba, S]]
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[[Category: Koshiba S]]
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[[Category: Structural genomic]]
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[[Category: Tanaka A]]
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[[Category: Tanaka, A]]
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[[Category: Tochio N]]
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[[Category: Tochio, N]]
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[[Category: Umehara T]]
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[[Category: Umehara, T]]
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[[Category: Watanabe S]]
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[[Category: Watanabe, S]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Yoneyama M]]
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[[Category: Yoneyama, M]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Transcription]]
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[[Category: Zfat zinc finger 1]]
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Current revision

Solution structure of the 5th C2H2 zinc finger of mouse Zinc finger protein 406

PDB ID 2elw

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