2pfc

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<StructureSection load='2pfc' size='340' side='right'caption='[[2pfc]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2pfc' size='340' side='right'caption='[[2pfc]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PFC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PFC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [https://pdbe.org/2pfc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [https://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [https://pdbe.org/2pfc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [https://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FCOT_MYCTU FCOT_MYCTU] Thiesterase that shows a preference for long chain fatty acyl groups. In vitro, cleaves the thioester linkage of palmitoyl-CoA, stearoyl-CoA, lauroyl-CoA and hexanoyl-CoA (PubMed:17524985). Contains low levels of trans-enoyl hydratase activity (PubMed:19136596).<ref>PMID:17524985</ref> <ref>PMID:19136596</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Sacchettini, J C]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Wang, F]]
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[[Category: Sacchettini JC]]
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[[Category: Thioesterase]]
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[[Category: Wang F]]
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[[Category: Tuberculosis]]
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[[Category: Unknown function]]
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[[Category: Virulence]]
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Revision as of 16:39, 13 December 2023

Structure of Mycobacterium tuberculosis Rv0098

PDB ID 2pfc

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