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5oqn

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==Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex bound to DNA (short kleisin loop)==
==Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex bound to DNA (short kleisin loop)==
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<StructureSection load='5oqn' size='340' side='right' caption='[[5oqn]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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<StructureSection load='5oqn' size='340' side='right'caption='[[5oqn]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5oqn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OQN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5oqn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OQN FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YCG1, YCS5, YDR325W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), BRN1, YBL097W, YBL0830 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oqn OCA], [http://pdbe.org/5oqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oqn RCSB], [http://www.ebi.ac.uk/pdbsum/5oqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oqn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5oqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oqn OCA], [https://pdbe.org/5oqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5oqn RCSB], [https://www.ebi.ac.uk/pdbsum/5oqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5oqn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CND3_YEAST CND3_YEAST]] Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase. [[http://www.uniprot.org/uniprot/CND2_YEAST CND2_YEAST]] Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase.<ref>PMID:10749930</ref> <ref>PMID:10749931</ref>
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[https://www.uniprot.org/uniprot/CND3_YEAST CND3_YEAST] Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5oqn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5oqn" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Condensin|Condensin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
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[[Category: Large Structures]]
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[[Category: Haering, C H]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Hassler, M]]
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[[Category: Synthetic construct]]
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[[Category: Kschonsak, M]]
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[[Category: Haering CH]]
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[[Category: Cell cycle]]
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[[Category: Hassler M]]
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[[Category: Dna-binding]]
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[[Category: Kschonsak M]]
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[[Category: Heat repeat]]
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[[Category: Kleisin]]
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[[Category: Smc complex]]
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Current revision

Crystal structure of the S. cerevisiae condensin Ycg1-Brn1 subcomplex bound to DNA (short kleisin loop)

PDB ID 5oqn

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