Thiol peroxidase
From Proteopedia
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<StructureSection load='3hvs' size='350' side='right' scene='' caption='E. coli thiol peroxidase dimer complex with citric acid (PDB code [[3hvs]])'> | <StructureSection load='3hvs' size='350' side='right' scene='' caption='E. coli thiol peroxidase dimer complex with citric acid (PDB code [[3hvs]])'> | ||
| - | '''Thiol peroxidase''' (TPX) is part of an oxidative stress defense system that uses thioredoxin and thioredoxin reductase to reduce alkyl hydroperoxides. TPX is an antioxidant which reduces peroxides and inhibits hydrogen peroxide response. TPX is also implicated in activation of transcription factors and signaling<ref>PMID:20649470</ref>. See also [[Bacterioferritin comigratory protein]]. | + | '''Thiol peroxidase''' or '''peroxiredoxin''' (TPX) is part of an oxidative stress defense system that uses thioredoxin and thioredoxin reductase to reduce alkyl hydroperoxides. TPX is an antioxidant which reduces peroxides and inhibits hydrogen peroxide response. TPX is also implicated in activation of transcription factors and signaling<ref>PMID:20649470</ref>. See also [[Bacterioferritin comigratory protein]]. |
</StructureSection> | </StructureSection> | ||
==3D structures of thiol peroxidase== | ==3D structures of thiol peroxidase== | ||
Revision as of 11:13, 18 December 2023
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3D structures of thiol peroxidase
Updated on 18-December-2023
1q98 – TPX – Haemophilus influenzae
1qxh, 3hvs, 3i43, 4af2 – EcTPX – Escherichia coli
3hvv, 3hvx - EcTPX (mutant)
1xvq – TPX – Mycobacterium tuberculosis
2xpd, 2xpe, 3zrd, 3zre – YpTPX – Yersinia pseudotuberculosis
2yjh - YpTPX (mutant)
4gqc, 4gqf – TPX – Aeropyrum pernix
6udg – TPX – Elizabethkingia anophelis
References
- ↑ Flohe L, Toppo S, Cozza G, Ursini F. A comparison of thiol peroxidase mechanisms. Antioxid Redox Signal. 2011 Aug 1;15(3):763-80. doi: 10.1089/ars.2010.3397. Epub , 2010 Nov 1. PMID:20649470 doi:http://dx.doi.org/10.1089/ars.2010.3397
