8i9q
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | The | + | ==The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state== |
- | + | <StructureSection load='8i9q' size='340' side='right'caption='[[8i9q]], [[Resolution|resolution]] 4.22Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8i9q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I9Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I9Q FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.22Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i9q OCA], [https://pdbe.org/8i9q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i9q RCSB], [https://www.ebi.ac.uk/pdbsum/8i9q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i9q ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/TCPD_HUMAN TCPD_HUMAN] Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).<ref>PMID:20080638</ref> <ref>PMID:25467444</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Kim H]] | ||
+ | [[Category: Lim S]] | ||
+ | [[Category: Park J]] | ||
+ | [[Category: Roh SH]] |
Current revision
The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state
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Categories: Homo sapiens | Large Structures | Kim H | Lim S | Park J | Roh SH