2wrt
From Proteopedia
(Difference between revisions)
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<StructureSection load='2wrt' size='340' side='right'caption='[[2wrt]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='2wrt' size='340' side='right'caption='[[2wrt]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2wrt]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2wrt]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Fasciola_hepatica Fasciola hepatica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WRT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WRT FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wrt OCA], [https://pdbe.org/2wrt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wrt RCSB], [https://www.ebi.ac.uk/pdbsum/2wrt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wrt ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wrt OCA], [https://pdbe.org/2wrt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wrt RCSB], [https://www.ebi.ac.uk/pdbsum/2wrt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wrt ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/GST26_FASHE GST26_FASHE] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Fasciola hepatica]] |
| - | + | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Brophy | + | [[Category: Brophy PM]] |
| - | [[Category: Isupov | + | [[Category: Isupov MN]] |
| - | [[Category: LaCourse | + | [[Category: LaCourse EJ]] |
| - | [[Category: Line | + | [[Category: Line K]] |
| - | [[Category: Littlechild | + | [[Category: Littlechild JA]] |
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Current revision
The 2.4 Angstrom structure of the Fasciola hepatica mu class GST, GST26
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