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2xu3
From Proteopedia
(Difference between revisions)
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<StructureSection load='2xu3' size='340' side='right'caption='[[2xu3]], [[Resolution|resolution]] 0.90Å' scene=''> | <StructureSection load='2xu3' size='340' side='right'caption='[[2xu3]], [[Resolution|resolution]] 0.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xu3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2xu3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XU3 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=XU3:(2S,4R)-4-(2-CHLOROPHENYL)SULFONYL-1-[1-(5-CHLOROTHIOPHEN-2-YL)CYCLOPROPYL]CARBONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]PYRROLIDINE-2-CARBOXAMIDE'>XU3</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.9Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=XU3:(2S,4R)-4-(2-CHLOROPHENYL)SULFONYL-1-[1-(5-CHLOROTHIOPHEN-2-YL)CYCLOPROPYL]CARBONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]PYRROLIDINE-2-CARBOXAMIDE'>XU3</scene></td></tr> | |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu3 OCA], [https://pdbe.org/2xu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xu3 RCSB], [https://www.ebi.ac.uk/pdbsum/2xu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xu3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu3 OCA], [https://pdbe.org/2xu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xu3 RCSB], [https://www.ebi.ac.uk/pdbsum/2xu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xu3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. | |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | + | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Banner | + | [[Category: Banner DW]] |
| - | [[Category: Benz | + | [[Category: Benz JM]] |
| - | [[Category: Haap | + | [[Category: Haap W]] |
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Current revision
CATHEPSIN L WITH A NITRILE INHIBITOR
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