2xur
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2xur' size='340' side='right'caption='[[2xur]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2xur' size='340' side='right'caption='[[2xur]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xur]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2xur]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XUR FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xur OCA], [https://pdbe.org/2xur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xur RCSB], [https://www.ebi.ac.uk/pdbsum/2xur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xur ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xur OCA], [https://pdbe.org/2xur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xur RCSB], [https://www.ebi.ac.uk/pdbsum/2xur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xur ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/DPO3B_ECOLI DPO3B_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA. | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 18: | Line 18: | ||
</div> | </div> | ||
<div class="pdbe-citations 2xur" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2xur" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli]] |
| - | + | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bjoras | + | [[Category: Bjoras M]] |
| - | [[Category: Dalhus | + | [[Category: Dalhus B]] |
| - | [[Category: Flaatten | + | [[Category: Flaatten I]] |
| - | [[Category: Johnsen | + | [[Category: Johnsen L]] |
[[Category: Morigen]] | [[Category: Morigen]] | ||
| - | [[Category: Skarstad | + | [[Category: Skarstad K]] |
| - | [[Category: Waldminghaus | + | [[Category: Waldminghaus T]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
| |||||||||||
