3zei
From Proteopedia
(Difference between revisions)
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<StructureSection load='3zei' size='340' side='right'caption='[[3zei]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='3zei' size='340' side='right'caption='[[3zei]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3zei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3zei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZEI FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AWH:3-[(Z)-[(5Z)-5-[[2-(2-HYDROXY-2-OXOETHYLOXY)PHENYL]METHYLIDENE]-3-METHYL-4-OXIDANYLIDENE-1,3-THIAZOLIDIN-2-YLIDENE]AMINO]BENZOIC+ACID'>AWH</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AWH:3-[(Z)-[(5Z)-5-[[2-(2-HYDROXY-2-OXOETHYLOXY)PHENYL]METHYLIDENE]-3-METHYL-4-OXIDANYLIDENE-1,3-THIAZOLIDIN-2-YLIDENE]AMINO]BENZOIC+ACID'>AWH</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zei OCA], [https://pdbe.org/3zei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zei RCSB], [https://www.ebi.ac.uk/pdbsum/3zei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zei ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zei OCA], [https://pdbe.org/3zei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zei RCSB], [https://www.ebi.ac.uk/pdbsum/3zei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zei ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/CYSK_MYCTU CYSK_MYCTU] Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide. | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cysteine synthase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis]] |
| - | [[Category: | + | [[Category: Poyraz O]] |
| - | [[Category: | + | [[Category: Schneider G]] |
| - | [[Category: | + | [[Category: Schnell R]] |
| - | + | ||
Current revision
Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor
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