This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3zlf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:05, 20 December 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3zlf' size='340' side='right'caption='[[3zlf]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='3zlf' size='340' side='right'caption='[[3zlf]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Strp6 Strp6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3zlf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_MGAS10394 Streptococcus pyogenes MGAS10394]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZLF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZLF FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zlg|3zlg]], [[3zlh|3zlh]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [https://pdbe.org/3zlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [https://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zlf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zlf OCA], [https://pdbe.org/3zlf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zlf RCSB], [https://www.ebi.ac.uk/pdbsum/3zlf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zlf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6]] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>
+
[https://www.uniprot.org/uniprot/ENO_STRP6 ENO_STRP6] Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. Binds plasminogen when expressed on the bacterial cell surface, potentially allowing the bacterium to acquire surface-associated proteolytic activity, which in turn contributes to tissue invasion and virulence.<ref>PMID:9603964</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 28: Line 27:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Phosphopyruvate hydratase]]
+
[[Category: Streptococcus pyogenes MGAS10394]]
-
[[Category: Strp6]]
+
[[Category: Aquilina JA]]
-
[[Category: Aquilina, J A]]
+
[[Category: Bertozzi C]]
-
[[Category: Bertozzi, C]]
+
[[Category: Casey LW]]
-
[[Category: Casey, L W]]
+
[[Category: Cork AJ]]
-
[[Category: Cork, A J]]
+
[[Category: Ericsson DJ]]
-
[[Category: Ericsson, D J]]
+
[[Category: Kobe B]]
-
[[Category: Kobe, B]]
+
[[Category: Law RHP]]
-
[[Category: Law, R H.P]]
+
[[Category: Stamp A]]
-
[[Category: Stamp, A]]
+
[[Category: Valkov E]]
-
[[Category: Valkov, E]]
+
[[Category: Walker MJ]]
-
[[Category: Walker, M J]]
+
[[Category: Whisstock JC]]
-
[[Category: Whisstock, J C]]
+
-
[[Category: Lyase]]
+
-
[[Category: Plasminogen-binding]]
+

Current revision

Structure of group A Streptococcal enolase K312A mutant

PDB ID 3zlf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3zlf"
Personal tools