3zs4

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Current revision (11:11, 20 December 2023) (edit) (undo)
 
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<StructureSection load='3zs4' size='340' side='right'caption='[[3zs4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3zs4' size='340' side='right'caption='[[3zs4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zs4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZS4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zs4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZS4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PR:PHOSPHORIC+ACID+MONO-[5-({[5-CARBAMOYL-3-(5-PHOSPHONOOXY-5-DEOXY-RIBOFURANOSYL)-+3H-IMIDAZOL-4-YLAMINO]-METHYL}-AMINO)-2,3,4-TRIHYDROXY-PENTYL]+ESTER'>1PR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2y89|2y89]], [[2y85|2y85]], [[2y88|2y88]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PR:PHOSPHORIC+ACID+MONO-[5-({[5-CARBAMOYL-3-(5-PHOSPHONOOXY-5-DEOXY-RIBOFURANOSYL)-+3H-IMIDAZOL-4-YLAMINO]-METHYL}-AMINO)-2,3,4-TRIHYDROXY-PENTYL]+ESTER'>1PR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs4 OCA], [https://pdbe.org/3zs4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zs4 RCSB], [https://www.ebi.ac.uk/pdbsum/3zs4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zs4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zs4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zs4 OCA], [https://pdbe.org/3zs4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zs4 RCSB], [https://www.ebi.ac.uk/pdbsum/3zs4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zs4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/HIS4_MYCTU HIS4_MYCTU]] Involved in both the histidine and tryptophan biosynthetic pathways.
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[https://www.uniprot.org/uniprot/HIS4_MYCTU HIS4_MYCTU] Involved in both the histidine and tryptophan biosynthetic pathways.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Due, A V]]
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[[Category: Due AV]]
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[[Category: Geerlof, A]]
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[[Category: Geerlof A]]
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[[Category: Kuper, J]]
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[[Category: Kuper J]]
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[[Category: Wilmanns, M]]
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[[Category: Wilmanns M]]
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[[Category: Aromatic amino acid biosynthesis]]
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[[Category: Histidine biosynthesis]]
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[[Category: Isomerase]]
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[[Category: Tim barrel]]
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[[Category: Tryptophan biosynthesis]]
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Current revision

CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE WITH BOUND PRFAR

PDB ID 3zs4

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