3zyh

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Current revision (11:16, 20 December 2023) (edit) (undo)
 
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<StructureSection load='3zyh' size='340' side='right'caption='[[3zyh]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='3zyh' size='340' side='right'caption='[[3zyh]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zyh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zyh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZYH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G0S:3-(BETA-D-GALACTOPYRANOSYLTHIO)PROPANOIC+ACID'>G0S</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.501&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vxj|2vxj]], [[1oko|1oko]], [[1uoj|1uoj]], [[2wyf|2wyf]], [[1l7l|1l7l]], [[3zyf|3zyf]], [[3zyb|3zyb]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G0S:3-(BETA-D-GALACTOPYRANOSYLTHIO)PROPANOIC+ACID'>G0S</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lecA, pa1L, PA2570 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyh OCA], [https://pdbe.org/3zyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyh RCSB], [https://www.ebi.ac.uk/pdbsum/3zyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zyh OCA], [https://pdbe.org/3zyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zyh RCSB], [https://www.ebi.ac.uk/pdbsum/3zyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zyh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE]] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
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[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pseae]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Bergmann, M]]
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[[Category: Bergmann M]]
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[[Category: Cacciarini, M]]
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[[Category: Cacciarini M]]
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[[Category: Camara, M]]
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[[Category: Camara M]]
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[[Category: Darbre, T]]
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[[Category: Darbre T]]
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[[Category: Garg, D]]
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[[Category: Garg D]]
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[[Category: Hurley, M]]
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[[Category: Hurley M]]
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[[Category: Kadam, R U]]
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[[Category: Kadam RU]]
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[[Category: Nativi, C]]
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[[Category: Nativi C]]
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[[Category: Reymond, J L]]
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[[Category: Reymond J-L]]
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[[Category: Sattler, M]]
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[[Category: Sattler M]]
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[[Category: Smyth, A R]]
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[[Category: Smyth AR]]
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[[Category: Stocker, A]]
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[[Category: Stocker A]]
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[[Category: Swiderska, M A]]
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[[Category: Swiderska MA]]
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[[Category: Williams, P]]
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[[Category: Williams P]]
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[[Category: Adhesin]]
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[[Category: Galactose-specific]]
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[[Category: Galactoside]]
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[[Category: Glycosphingolipid-antigen]]
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[[Category: Sugar binding protein-inhibitor complex]]
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Current revision

CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALBG0 AT 1.5 A RESOLUTION

PDB ID 3zyh

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