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4a6s
From Proteopedia
(Difference between revisions)
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<StructureSection load='4a6s' size='340' side='right'caption='[[4a6s]], [[Resolution|resolution]] 2.15Å' scene=''> | <StructureSection load='4a6s' size='340' side='right'caption='[[4a6s]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4a6s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4a6s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A6S FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GS9:NAPHTHALEN-2-YL+1-THIO-BETA-D-GALACTOPYRANOSIDE'>GS9</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a6s OCA], [https://pdbe.org/4a6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a6s RCSB], [https://www.ebi.ac.uk/pdbsum/4a6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a6s ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a6s OCA], [https://pdbe.org/4a6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a6s RCSB], [https://www.ebi.ac.uk/pdbsum/4a6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a6s ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Pseudomonas aeruginosa PAO1]] |
| - | [[Category: Blanchard | + | [[Category: Blanchard B]] |
| - | [[Category: Chiao | + | [[Category: Chiao TS]] |
| - | [[Category: Ganne | + | [[Category: Ganne G]] |
| - | [[Category: Giguere | + | [[Category: Giguere D]] |
| - | [[Category: Imberty | + | [[Category: Imberty A]] |
| - | [[Category: Rodrigue | + | [[Category: Rodrigue J]] |
| - | [[Category: Roy | + | [[Category: Roy R]] |
| - | [[Category: Saucier | + | [[Category: Saucier C]] |
| - | [[Category: Varrot | + | [[Category: Varrot A]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structure of the PAIL lectin from Pseudomonas aeruginosa in complex with 2-Naphtyl-1-thio-beta-D-galactopyranoside
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