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1p5j

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[[Image:1p5j.gif|left|200px]]
[[Image:1p5j.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1p5j |SIZE=350|CAPTION= <scene name='initialview01'>1p5j</scene>, resolution 2.5&Aring;
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The line below this paragraph, containing "STRUCTURE_1p5j", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5&#39;-PHOSPHATE'>PLP</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/L-serine_ammonia-lyase L-serine ammonia-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.1.17 4.3.1.17] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1p5j| PDB=1p5j | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p5j OCA], [http://www.ebi.ac.uk/pdbsum/1p5j PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1p5j RCSB]</span>
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}}
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'''Crystal Structure Analysis of Human Serine Dehydratase'''
'''Crystal Structure Analysis of Human Serine Dehydratase'''
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[[Category: Rao, Z.]]
[[Category: Rao, Z.]]
[[Category: Sun, L.]]
[[Category: Sun, L.]]
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[[Category: lyase]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:42:41 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:55:10 2008''
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Revision as of 01:42, 3 May 2008

Image:1p5j.gif

Template:STRUCTURE 1p5j

Crystal Structure Analysis of Human Serine Dehydratase


Overview

L-Serine dehydratase (SDH) catalyzes the pyridoxal phosphate (PLP) dependent deamination of L-serine to yield pyruvate. Recombinant human serine dehydratase was crystallized by the hanging-drop vapour-diffusion method. Crystals were grown at 291 K using (NH4)(2)SO4 as precipitant. Diffraction data were obtained to a resolution of 2.5 A from a single frozen crystal using Cu Kalpha radiation. The crystal belongs to space group I422, with unit-cell parameters a = 157.4, b = 157.4, c = 59.2 A, alpha = beta = gamma = 90 degrees. The asymmetric unit contains one molecule and has a solvent content of about 46%.

About this Structure

1P5J is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystallization and preliminary crystallographic analysis of human serine dehydratase., Sun L, Li X, Dong Y, Yang M, Liu Y, Han X, Zhang X, Pang H, Rao Z, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2297-9. Epub 2003, Nov 27. PMID:14646100 Page seeded by OCA on Sat May 3 04:42:41 2008

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