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4a7d

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a7d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A7D FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a7d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A7D FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.497&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1w6z|1w6z]], [[1kxx|1kxx]], [[2ybi|2ybi]], [[2ybn|2ybn]], [[4lyo|4lyo]], [[3lyo|3lyo]], [[1t6v|1t6v]], [[1kip|1kip]], [[1ic7|1ic7]], [[1vds|1vds]], [[1lzt|1lzt]], [[2xbr|2xbr]], [[1kir|1kir]], [[1lys|1lys]], [[132l|132l]], [[1e8l|1e8l]], [[1bwj|1bwj]], [[1yil|1yil]], [[1heo|1heo]], [[1sfg|1sfg]], [[1kxw|1kxw]], [[2c8o|2c8o]], [[2x0a|2x0a]], [[1yl1|1yl1]], [[1sf4|1sf4]], [[1g7l|1g7l]], [[1ior|1ior]], [[1h87|1h87]], [[1ljg|1ljg]], [[3lyt|3lyt]], [[1dpx|1dpx]], [[1iot|1iot]], [[1v7s|1v7s]], [[1ja6|1ja6]], [[1jis|1jis]], [[1ir8|1ir8]], [[2w1m|2w1m]], [[1uic|1uic]], [[1ykz|1ykz]], [[1xgq|1xgq]], [[1uie|1uie]], [[2war|2war]], [[1lji|1lji]], [[1lj3|1lj3]], [[1dpw|1dpw]], [[8lyz|8lyz]], [[2iff|2iff]], [[2lyo|2lyo]], [[1bwi|1bwi]], [[1g7h|1g7h]], [[1jj0|1jj0]], [[1lks|1lks]], [[1rfp|1rfp]], [[5lyt|5lyt]], [[1jiy|1jiy]], [[1sfb|1sfb]], [[1ir7|1ir7]], [[1iee|1iee]], [[1xei|1xei]], [[1hel|1hel]], [[1xek|1xek]], [[1at6|1at6]], [[1ljf|1ljf]], [[2ydg|2ydg]], [[1mlc|1mlc]], [[2b5z|2b5z]], [[1f10|1f10]], [[1lsz|1lsz]], [[193l|193l]], [[2ybm|2ybm]], [[1ljk|1ljk]], [[6lyt|6lyt]], [[1sq2|1sq2]], [[1zmy|1zmy]], [[2ybh|2ybh]], [[1vdq|1vdq]], [[2d91|2d91]], [[2xth|2xth]], [[1lje|1lje]], [[1b2k|1b2k]], [[1lze|1lze]], [[9lyz|9lyz]], [[2ybj|2ybj]], [[1aki|1aki]], [[1hen|1hen]], [[1uia|1uia]], [[1yik|1yik]], [[1xfp|1xfp]], [[2d6b|2d6b]], [[1lpi|1lpi]], [[1ndg|1ndg]], [[1lsd|1lsd]], [[1flw|1flw]], [[2blx|2blx]], [[6lyz|6lyz]], [[1lsg|1lsg]], [[1nbz|1nbz]], [[4lyt|4lyt]], [[3hfm|3hfm]], [[1ved|1ved]], [[1jit|1jit]], [[1lzn|1lzn]], [[1uuz|1uuz]], [[1lyz|1lyz]], [[1ja2|1ja2]], [[1wtn|1wtn]], [[2d4i|2d4i]], [[2xbs|2xbs]], [[2fbb|2fbb]], [[1fdl|1fdl]], [[2lym|2lym]], [[1lz9|1lz9]], [[1lse|1lse]], [[1lzh|1lzh]], [[1gxx|1gxx]], [[1lsm|1lsm]], [[3lym|3lym]], [[7lyz|7lyz]], [[1jj3|1jj3]], [[1yky|1yky]], [[1t3p|1t3p]], [[1heq|1heq]], [[1kiq|1kiq]], [[1kxy|1kxy]], [[2lzh|2lzh]], [[1uih|1uih]], [[2w1l|2w1l]], [[2bly|2bly]], [[1b0d|1b0d]], [[1g7j|1g7j]], [[1her|1her]], [[1bhz|1bhz]], [[1wtm|1wtm]], [[1hep|1hep]], [[1ioq|1ioq]], [[1nby|1nby]], [[1jtt|1jtt]], [[1qio|1qio]], [[1lza|1lza]], [[1xgp|1xgp]], [[1ps5|1ps5]], [[1gwd|1gwd]], [[3zvq|3zvq]], [[1v7t|1v7t]], [[1jpo|1jpo]], [[1h6m|1h6m]], [[1dqj|1dqj]], [[2a7d|2a7d]], [[1j1p|1j1p]], [[1ljj|1ljj]], [[1z55|1z55]], [[2c8p|2c8p]], [[1lsb|1lsb]], [[1f0w|1f0w]], [[2w1x|2w1x]], [[1lzg|1lzg]], [[1flq|1flq]], [[1lzc|1lzc]], [[1jj1|1jj1]], [[1rcm|1rcm]], [[2ybl|2ybl]], [[1uid|1uid]], [[1yqv|1yqv]], [[1hsx|1hsx]], [[1bgi|1bgi]], [[1lcn|1lcn]], [[1lzd|1lzd]], [[1hew|1hew]], [[2cds|2cds]], [[2vb1|2vb1]], [[2aub|2aub]], [[1hf4|1hf4]], [[1uib|1uib]], [[1ir9|1ir9]], [[2cgi|2cgi]], [[1ios|1ios]], [[1j1x|1j1x]], [[1rjc|1rjc]], [[1uc0|1uc0]], [[1azf|1azf]], [[1ic4|1ic4]], [[1ljh|1ljh]], [[4lyz|4lyz]], [[1gpq|1gpq]], [[2a6u|2a6u]], [[2d4k|2d4k]], [[1xej|1xej]], [[1ja7|1ja7]], [[1mel|1mel]], [[1ri8|1ri8]], [[1uig|1uig]], [[1bvx|1bvx]], [[1qtk|1qtk]], [[1c10|1c10]], [[1lkr|1lkr]], [[1lyo|1lyo]], [[2xjw|2xjw]], [[1hsw|1hsw]], [[1n4f|1n4f]], [[2w1y|2w1y]], [[1jto|1jto]], [[1g7m|1g7m]], [[1sf7|1sf7]], [[1lsf|1lsf]], [[1fn5|1fn5]], [[2d4j|2d4j]], [[5lyz|5lyz]], [[1c08|1c08]], [[3lzt|3lzt]], [[1ndm|1ndm]], [[1sf6|1sf6]], [[3lyz|3lyz]], [[1bvk|1bvk]], [[1uif|1uif]], [[1vau|1vau]], [[2lyz|2lyz]], [[1fly|1fly]], [[1lma|1lma]], [[1hc0|1hc0]], [[1j1o|1j1o]], [[1yl0|1yl0]], [[2lzt|2lzt]], [[1a2y|1a2y]], [[4lzt|4lzt]], [[1uco|1uco]], [[1lsy|1lsy]], [[1lsa|1lsa]], [[5lym|5lym]], [[1gxv|1gxv]], [[1p2c|1p2c]], [[1ic5|1ic5]], [[1ua6|1ua6]], [[1at5|1at5]], [[1vfb|1vfb]], [[1f3j|1f3j]], [[1vat|1vat]], [[1hem|1hem]], [[1lj4|1lj4]], [[1ja4|1ja4]], [[2a7f|2a7f]], [[4lym|4lym]], [[1flu|1flu]], [[194l|194l]], [[1lz8|1lz8]], [[1ykx|1ykx]], [[1bwh|1bwh]], [[1vdt|1vdt]], [[2hfm|2hfm]], [[1io5|1io5]], [[1lsn|1lsn]], [[1g7i|1g7i]], [[2bpu|2bpu]], [[1lzb|1lzb]], [[1lsc|1lsc]], [[1vdp|1vdp]], [[4a7e|4a7e]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a7d OCA], [https://pdbe.org/4a7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a7d RCSB], [https://www.ebi.ac.uk/pdbsum/4a7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a7d ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a7d OCA], [https://pdbe.org/4a7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a7d RCSB], [https://www.ebi.ac.uk/pdbsum/4a7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a7d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysozyme]]
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[[Category: Burkhardt A]]
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[[Category: Burkhardt, A]]
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[[Category: Hohenberg H]]
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[[Category: Hohenberg, H]]
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[[Category: Meents A]]
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[[Category: Meents, A]]
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[[Category: Panneerselvam S]]
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[[Category: Panneerselvam, S]]
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[[Category: Reimer R]]
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[[Category: Reimer, R]]
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[[Category: Wagner A]]
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[[Category: Wagner, A]]
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[[Category: Warmer M]]
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[[Category: Warmer, M]]
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[[Category: High-pressure cooling]]
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[[Category: High-pressure protein crystallography]]
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[[Category: Hydrolase]]
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Current revision

X-ray crystal structure of HEWL flash-cooled at high pressure

PDB ID 4a7d

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