4axo
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4axo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridioides_difficile_630 Clostridioides difficile 630]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AXO FirstGlance]. <br> | <table><tr><td colspan='2'>[[4axo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridioides_difficile_630 Clostridioides difficile 630]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AXO FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4axo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4axo OCA], [https://pdbe.org/4axo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4axo RCSB], [https://www.ebi.ac.uk/pdbsum/4axo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4axo ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4axo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4axo OCA], [https://pdbe.org/4axo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4axo RCSB], [https://www.ebi.ac.uk/pdbsum/4axo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4axo ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EUTQ_CLOD6 EUTQ_CLOD6] A bidirectional acetate kinase that may drive flux through the ethanolamine (EA) degradation pathway under anoxic conditions found when this bacteria infects the host intestine. It may generate ATP that can be used by other enzymes (EutA and EutT) in the eut pathway. Might serve as an assembly hub for bacterial microcompartment (BMC) shell proteins (By similarity). Overexpression in E.coli leads to lamellar structures that inhibit cell division (PubMed:23144756). Expression of the eut operon may allow this bacteria to use EA as a carbon, nitrogen and energy source (Probable).[UniProtKB:Q9ZFV5]<ref>PMID:23144756</ref> <ref>PMID:23144756</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Clostridioides difficile 630]] | [[Category: Clostridioides difficile 630]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Faulds-Pain | + | [[Category: Faulds-Pain A]] |
| - | [[Category: Lewis | + | [[Category: Lewis RJ]] |
| - | [[Category: Marles-Wright | + | [[Category: Marles-Wright J]] |
| - | [[Category: Pitts | + | [[Category: Pitts AC]] |
| - | [[Category: Tuck | + | [[Category: Tuck LR]] |
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Current revision
Structure of the Clostridium difficile EutQ protein
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