4bez

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Current revision (11:49, 20 December 2023) (edit) (undo)
 
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<StructureSection load='4bez' size='340' side='right'caption='[[4bez]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='4bez' size='340' side='right'caption='[[4bez]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4bez]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BEZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4bez]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BEZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4bey|4bey]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bez OCA], [https://pdbe.org/4bez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bez RCSB], [https://www.ebi.ac.uk/pdbsum/4bez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bez ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bez OCA], [https://pdbe.org/4bez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bez RCSB], [https://www.ebi.ac.uk/pdbsum/4bez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bez ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>
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[https://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Deupi, X]]
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[[Category: Deupi X]]
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[[Category: Gurevich, V V]]
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[[Category: Gurevich VV]]
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[[Category: Homan, K T]]
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[[Category: Homan KT]]
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[[Category: Ostermaier, M K]]
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[[Category: Ostermaier MK]]
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[[Category: Panneels, V]]
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[[Category: Panneels V]]
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[[Category: Schertler, G F.X]]
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[[Category: Schertler GFX]]
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[[Category: Singhal, A]]
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[[Category: Singhal A]]
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[[Category: Standfuss, J]]
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[[Category: Standfuss J]]
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[[Category: Tesmer, J J.G]]
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[[Category: Tesmer JJG]]
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[[Category: Veprintsev, D]]
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[[Category: Veprintsev D]]
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[[Category: Vishnivetskiy, S A]]
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[[Category: Vishnivetskiy SA]]
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[[Category: Active state]]
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[[Category: Congential stationary night blindness]]
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[[Category: Disease mutant]]
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[[Category: Gpcr]]
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[[Category: Membrane protein]]
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Current revision

Night blindness causing G90D rhodopsin in the active conformation

PDB ID 4bez

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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