Amlodipine

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Amlodipine, sold under the brand name Norvasc among others, is a calcium channel blocker medication used to treat high blood pressure, coronary artery disease (CAD)<ref name="a10">[https://www.drugs.com/monograph/amlodipine.html "Amlodipine Besylate".] Drugs.com. American Society of Hospital Pharmacists. Archived from the original on 4 June 2016. Retrieved 22 July 2016.</ref> See also [https://en.wikipedia.org/wiki/Amlodipine Amlodipine].
Amlodipine, sold under the brand name Norvasc among others, is a calcium channel blocker medication used to treat high blood pressure, coronary artery disease (CAD)<ref name="a10">[https://www.drugs.com/monograph/amlodipine.html "Amlodipine Besylate".] Drugs.com. American Society of Hospital Pharmacists. Archived from the original on 4 June 2016. Retrieved 22 July 2016.</ref> See also [https://en.wikipedia.org/wiki/Amlodipine Amlodipine].
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Amlodipine is a long-acting calcium channel antagonist that selectively inhibits calcium ion influx across cell membranes.[40] It targets L-type calcium channels in muscle cells and N-type calcium channels in the central nervous system which are involved in nociceptive signalling and pain perception.[41][42]
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Amlodipine is a long-acting calcium channel antagonist that selectively inhibits calcium ion influx across cell membranes.<ref name="a40">PMID:22469316</ref> It targets L-type calcium channels in muscle cells and N-type calcium channels in the central nervous system which are involved in nociceptive signalling and pain perception.<ref name="a41">[https://go.drugbank.com/drugs/DB00381 "Amlodipine".] www.drugbank.ca. Archived from the original on 31 January 2019. Retrieved 30 January 2019.</ref><ref name="a42">PMID:10332505</ref>[41][42]
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Revision as of 13:55, 21 December 2023

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References

  1. "Amlodipine Besylate". Drugs.com. American Society of Hospital Pharmacists. Archived from the original on 4 June 2016. Retrieved 22 July 2016.
  2. Ananchenko G, Novakovic J, Lewis J. Amlodipine besylate. Profiles Drug Subst Excip Relat Methodol. 2012;37:31-77. PMID:22469316 doi:10.1016/B978-0-12-397220-0.00002-7
  3. "Amlodipine". www.drugbank.ca. Archived from the original on 31 January 2019. Retrieved 30 January 2019.
  4. Clusin WT, Anderson ME. Calcium channel blockers: current controversies and basic mechanisms of action. Adv Pharmacol. 1999;46:253-96. PMID:10332505 doi:10.1016/s1054-3589(08)60473-1

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