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Amlodipine

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Amlodipine is a long-acting calcium channel antagonist that selectively inhibits calcium ion influx across cell membranes.<ref name="a40">PMID:22469316</ref> It targets L-type calcium channels in muscle cells and N-type calcium channels in the central nervous system which are involved in nociceptive signalling and pain perception.<ref name="a41">[https://go.drugbank.com/drugs/DB00381 "Amlodipine".] www.drugbank.ca. Archived from the original on 31 January 2019. Retrieved 30 January 2019.</ref><ref name="a42">PMID:10332505</ref>
Amlodipine is a long-acting calcium channel antagonist that selectively inhibits calcium ion influx across cell membranes.<ref name="a40">PMID:22469316</ref> It targets L-type calcium channels in muscle cells and N-type calcium channels in the central nervous system which are involved in nociceptive signalling and pain perception.<ref name="a41">[https://go.drugbank.com/drugs/DB00381 "Amlodipine".] www.drugbank.ca. Archived from the original on 31 January 2019. Retrieved 30 January 2019.</ref><ref name="a42">PMID:10332505</ref>
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<scene name='10/1017441/Cv/2'>Voltage-gated Ca(2+) channel with Amlodipine</scene> ([[5kmd]]).
</StructureSection>
</StructureSection>
== References ==
== References ==
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<references/>

Revision as of 14:14, 21 December 2023

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References

  1. "Amlodipine Besylate". Drugs.com. American Society of Hospital Pharmacists. Archived from the original on 4 June 2016. Retrieved 22 July 2016.
  2. Ananchenko G, Novakovic J, Lewis J. Amlodipine besylate. Profiles Drug Subst Excip Relat Methodol. 2012;37:31-77. PMID:22469316 doi:10.1016/B978-0-12-397220-0.00002-7
  3. "Amlodipine". www.drugbank.ca. Archived from the original on 31 January 2019. Retrieved 30 January 2019.
  4. Clusin WT, Anderson ME. Calcium channel blockers: current controversies and basic mechanisms of action. Adv Pharmacol. 1999;46:253-96. PMID:10332505 doi:10.1016/s1054-3589(08)60473-1

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