1p9n

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[[Image:1p9n.jpg|left|200px]]
[[Image:1p9n.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1p9n |SIZE=350|CAPTION= <scene name='initialview01'>1p9n</scene>, resolution 2.80&Aring;
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The line below this paragraph, containing "STRUCTURE_1p9n", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE= MobB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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-->
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|DOMAIN=
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{{STRUCTURE_1p9n| PDB=1p9n | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1p9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p9n OCA], [http://www.ebi.ac.uk/pdbsum/1p9n PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1p9n RCSB]</span>
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}}
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'''Crystal structure of Escherichia coli MobB.'''
'''Crystal structure of Escherichia coli MobB.'''
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[[Category: Rangarajan, S E.]]
[[Category: Rangarajan, S E.]]
[[Category: Tocilj, A.]]
[[Category: Tocilj, A.]]
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[[Category: bsgi]]
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[[Category: Bsgi]]
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[[Category: crystal structure]]
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[[Category: Crystal structure]]
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[[Category: mobb]]
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[[Category: Mobb]]
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[[Category: molybdopterin cofactor biosynthesis]]
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[[Category: Molybdopterin cofactor biosynthesis]]
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[[Category: montreal-kingston bacterial structural genomics initiative]]
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[[Category: Montreal-kingston bacterial structural genomics initiative]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:51:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:56:50 2008''
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Revision as of 01:51, 3 May 2008

Image:1p9n.jpg

Template:STRUCTURE 1p9n

Crystal structure of Escherichia coli MobB.


Overview

The crystal structure of Escherichia coli MobB, an enzyme involved in the final step of molybdenum-cofactor biosynthesis, forms intertwined dimers. Each molecule consists of two segments and requires the second monomer for stable folding. Dimerization buries a quarter of the solvent-accessible area of the monomer. These dimers assemble into a hexagonal lattice with P6(4)22 symmetry and occupy only approximately 25% of the unit-cell volume. The symmetry-related dimers associate tightly into a helical structure with a diameter of 250 A and a pitch of 98 A. Two such helices are intertwined, shifted by 49 A along the sixfold axis. Within the crystal, these helices form thin-walled cylinders with an external diameter of 250 A and an internal diameter of 190 A. Their center is filled with solvent. These cylinders pack closely together, forming a hexagonal lattice with the highest possible packing density. This arrangement of dimers allows extensive intermolecular contacts with 75% solvent content in the crystal.

About this Structure

1P9N is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Molecules of Escherichia coli MobB assemble into densely packed hollow cylinders in a crystal lattice with 75% solvent content., Rangarajan SE, Tocilj A, Li Y, Iannuzzi P, Matte A, Cygler M, Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2348-52. Epub 2003, Nov 27. PMID:14646116 Page seeded by OCA on Sat May 3 04:51:20 2008

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