1pa4

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[[Image:1pa4.gif|left|200px]]
[[Image:1pa4.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1pa4 |SIZE=350|CAPTION= <scene name='initialview01'>1pa4</scene>
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The line below this paragraph, containing "STRUCTURE_1pa4", creates the "Structure Box" on the page.
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|SITE=
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|GENE= MPN156 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2104 Mycoplasma pneumoniae])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0858 RbfA]</span>
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{{STRUCTURE_1pa4| PDB=1pa4 | SCENE= }}
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|RELATEDENTRY=[[1kkg|1KKG]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pa4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pa4 OCA], [http://www.ebi.ac.uk/pdbsum/1pa4 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1pa4 RCSB]</span>
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'''Solution structure of a putative ribosome-binding factor from Mycoplasma pneumoniae (MPN156)'''
'''Solution structure of a putative ribosome-binding factor from Mycoplasma pneumoniae (MPN156)'''
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[[Category: Wemmer, D E.]]
[[Category: Wemmer, D E.]]
[[Category: Yokota, H.]]
[[Category: Yokota, H.]]
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[[Category: berkeley structural genomics center]]
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[[Category: Berkeley structural genomics center]]
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[[Category: bsgc structure funded by nih]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: distant homology]]
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[[Category: Distant homology]]
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[[Category: protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: psi]]
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[[Category: Psi]]
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[[Category: ribosome-binding factor]]
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[[Category: Ribosome-binding factor]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:52:29 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:57:01 2008''
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Revision as of 01:52, 3 May 2008

Image:1pa4.gif

Template:STRUCTURE 1pa4

Solution structure of a putative ribosome-binding factor from Mycoplasma pneumoniae (MPN156)


Overview

The solution structure of MPN156, a ribosome-binding factor A (RBFA) protein family member from Mycoplasma pneumoniae, is presented. The structure, solved by nuclear magnetic resonance, has a type II KH fold typical of RNA binding proteins. Despite only approximately 20% sequence identity between MPN156 and another family member from Escherichia coli, the two proteins have high structural similarity. The comparison demonstrates that many of the conserved residues correspond to conserved elements in the structures. Compared to a structure based alignment, standard alignment methods based on sequence alone mispair a majority of amino acids in the two proteins. Implications of these discrepancies for sequence based structural modeling are discussed.

About this Structure

1PA4 is a Single protein structure of sequence from Mycoplasma pneumoniae. Full crystallographic information is available from OCA.

Reference

Solution structure of a putative ribosome binding protein from Mycoplasma pneumoniae and comparison to a distant homolog., Rubin SM, Pelton JG, Yokota H, Kim R, Wemmer DE, J Struct Funct Genomics. 2003;4(4):235-43. PMID:15185964 Page seeded by OCA on Sat May 3 04:52:29 2008

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