1flm

From Proteopedia

(Difference between revisions)

Current revision

DIMER OF FMN-BINDING PROTEIN FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F)

Structural highlights

1flm is a 2 chain structure with sequence from Desulfovibrio vulgaris str. 'Miyazaki F'. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.3Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FMNB_DESVM Functions as a redox protein with a potential of -325 mV.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The crystal structure of FMN-binding protein (FMN-bp) from Desulfovibrio vulgaris Miyazaki F was solved by the multiple isomorphous replacement method and refined to an R factor of 15.1% at 1.3 A resolution. FMN-bp exists in a dimeric form in the crystal, in contrast to the monomeric structure determined by NMR. R.m.s. deviations between the crystal structure and the solution structure are more than 2 A, which implies significant differences. There are some hydrophobic residues in the interface between the two monomers. In particular, Leu122 in the C-terminus has a close contact with the o-xylene moiety of FMN, while solvent molecules may cover the o-xylene moiety in the solution structure.

How do the x-ray structure and the NMR structure of FMN-binding protein differ?,Suto K, Kawagoe K, Shibata N, Morimoto Y, Higuchi Y, Kitamura M, Nakaya T, Yasuoka N Acta Crystallogr D Biol Crystallogr. 2000 Mar;56(Pt 3):368-71. PMID:10713530^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Suto K, Kawagoe K, Shibata N, Morimoto Y, Higuchi Y, Kitamura M, Nakaya T, Yasuoka N. How do the x-ray structure and the NMR structure of FMN-binding protein differ? Acta Crystallogr D Biol Crystallogr. 2000 Mar;56(Pt 3):368-71. PMID:10713530

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1flm"

@@ Line 3: / Line 3: @@
 <StructureSection load='1flm' size='340' side='right'caption='[[1flm]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1flm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Desvm Desvm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FLM FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1flm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._'Miyazaki_F' Desulfovibrio vulgaris str. 'Miyazaki F']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FLM FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1flm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flm OCA], [https://pdbe.org/1flm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1flm RCSB], [https://www.ebi.ac.uk/pdbsum/1flm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1flm ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[https://www.uniprot.org/uniprot/FMNB_DESVM FMNB_DESVM]] Functions as a redox protein with a potential of -325 mV.
+[https://www.uniprot.org/uniprot/FMNB_DESVM FMNB_DESVM] Functions as a redox protein with a potential of -325 mV.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 32: / Line 33: @@
 __TOC__
 </StructureSection>
-[[Category: Desvm]]
+[[Category: Desulfovibrio vulgaris str. 'Miyazaki F']]
 [[Category: Large Structures]]
-[[Category: Higuchi, Y]]
+[[Category: Higuchi Y]]
-[[Category: Kawagoe, K]]
+[[Category: Kawagoe K]]
-[[Category: Kitamura, M]]
+[[Category: Kitamura M]]
-[[Category: Morimoto, K]]
+[[Category: Morimoto K]]
-[[Category: Nakaya, T]]
+[[Category: Nakaya T]]
-[[Category: Shibata, N]]
+[[Category: Shibata N]]
-[[Category: Suto, K]]
+[[Category: Suto K]]
-[[Category: Yasuoka, N]]
+[[Category: Yasuoka N]]
-[[Category: Electron transport]]
-[[Category: Fmn binding]]

1flm

From Proteopedia

Current revision

DIMER OF FMN-BINDING PROTEIN FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F)

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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