1hhv

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==SOLUTION STRUCTURE OF VIRUS CHEMOKINE VMIP-II==
==SOLUTION STRUCTURE OF VIRUS CHEMOKINE VMIP-II==
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<StructureSection load='1hhv' size='340' side='right'caption='[[1hhv]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
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<StructureSection load='1hhv' size='340' side='right'caption='[[1hhv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1hhv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HHV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1hhv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_8_strain_GK18 Human herpesvirus 8 strain GK18]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HHV FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhv OCA], [https://pdbe.org/1hhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hhv RCSB], [https://www.ebi.ac.uk/pdbsum/1hhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhv OCA], [https://pdbe.org/1hhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hhv RCSB], [https://www.ebi.ac.uk/pdbsum/1hhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P]] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
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[https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human herpesvirus 8 strain GK18]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Fernandez, E]]
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[[Category: Fernandez E]]
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[[Category: Lolis, E]]
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[[Category: Lolis E]]
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[[Category: Navenot, J M]]
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[[Category: Navenot JM]]
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[[Category: Pepiper, S]]
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[[Category: Pepiper S]]
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[[Category: Schweitzer, B I]]
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[[Category: Schweitzer BI]]
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[[Category: Shao, W]]
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[[Category: Shao W]]
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[[Category: Thompson, D A]]
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[[Category: Thompson DA]]
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[[Category: Wilken, J]]
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[[Category: Wilken J]]
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[[Category: Receptor binding]]
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[[Category: Viral protein]]
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[[Category: Virus chemokine]]
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[[Category: Vmip-ii]]
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Revision as of 23:33, 27 December 2023

SOLUTION STRUCTURE OF VIRUS CHEMOKINE VMIP-II

PDB ID 1hhv

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