1izn

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Current revision (23:39, 27 December 2023) (edit) (undo)
 
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<StructureSection load='1izn' size='340' side='right'caption='[[1izn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1izn' size='340' side='right'caption='[[1izn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1izn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IZN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1izn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IZN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1izn OCA], [https://pdbe.org/1izn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1izn RCSB], [https://www.ebi.ac.uk/pdbsum/1izn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1izn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1izn OCA], [https://pdbe.org/1izn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1izn RCSB], [https://www.ebi.ac.uk/pdbsum/1izn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1izn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CAZA1_CHICK CAZA1_CHICK]] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line. [[https://www.uniprot.org/uniprot/CAPZB_CHICK CAPZB_CHICK]] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization.
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[https://www.uniprot.org/uniprot/CAZA1_CHICK CAZA1_CHICK] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Maeda, K]]
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[[Category: Maeda K]]
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[[Category: Maeda, Y]]
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[[Category: Maeda Y]]
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[[Category: Yamashita, A]]
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[[Category: Yamashita A]]
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[[Category: Actin filament barbed end capping]]
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[[Category: Capping protein]]
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[[Category: Heterodimer]]
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[[Category: Protein binding]]
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[[Category: Z-disk]]
[[Category: Z-disk]]

Current revision

Crystal Structure of Actin Filament Capping Protein CapZ

PDB ID 1izn

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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