1ujx
From Proteopedia
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==The forkhead associated (FHA) domain like structure from mouse polynucleotide kinase 3'-phosphatase== | ==The forkhead associated (FHA) domain like structure from mouse polynucleotide kinase 3'-phosphatase== | ||
| - | <StructureSection load='1ujx' size='340' side='right'caption='[[1ujx | + | <StructureSection load='1ujx' size='340' side='right'caption='[[1ujx]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1ujx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1ujx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UJX FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ujx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ujx OCA], [https://pdbe.org/1ujx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ujx RCSB], [https://www.ebi.ac.uk/pdbsum/1ujx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ujx ProSAT], [https://www.topsan.org/Proteins/RSGI/1ujx TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ujx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ujx OCA], [https://pdbe.org/1ujx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ujx RCSB], [https://www.ebi.ac.uk/pdbsum/1ujx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ujx ProSAT], [https://www.topsan.org/Proteins/RSGI/1ujx TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PNKP_MOUSE PNKP_MOUSE] Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Koshiba | + | [[Category: Koshiba S]] |
| - | + | [[Category: Tomizawa T]] | |
| - | [[Category: Tomizawa | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
The forkhead associated (FHA) domain like structure from mouse polynucleotide kinase 3'-phosphatase
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