1v5o

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Current revision (23:58, 27 December 2023) (edit) (undo)
 
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==Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein==
==Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein==
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<StructureSection load='1v5o' size='340' side='right'caption='[[1v5o]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1v5o' size='340' side='right'caption='[[1v5o]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1v5o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1v5o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5O FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 1700011N24 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5o OCA], [https://pdbe.org/1v5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5o RCSB], [https://www.ebi.ac.uk/pdbsum/1v5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5o ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5o TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5o OCA], [https://pdbe.org/1v5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5o RCSB], [https://www.ebi.ac.uk/pdbsum/1v5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5o ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5o TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DDI1_MOUSE DDI1_MOUSE] Probable aspartic protease (By similarity). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (By similarity).[UniProtKB:I7HUG0][UniProtKB:Q8WTU0]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Inoue, M]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T]]
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[[Category: Kigawa T]]
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[[Category: Koshiba, S]]
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[[Category: Koshiba S]]
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[[Category: Structural genomic]]
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[[Category: Tomizawa T]]
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[[Category: Tomizawa, T]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Zhao C]]
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[[Category: Zhao, C]]
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[[Category: Hypothetical protein]]
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[[Category: Rsgi]]
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[[Category: Ubiquitin-like fold]]
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[[Category: Unknown function]]
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Current revision

Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein

PDB ID 1v5o

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