1pcf

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[[Image:1pcf.gif|left|200px]]
[[Image:1pcf.gif|left|200px]]
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{{Structure
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{{STRUCTURE_1pcf| PDB=1pcf | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pcf OCA], [http://www.ebi.ac.uk/pdbsum/1pcf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1pcf RCSB]</span>
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'''HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN'''
'''HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN'''
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[[Category: Brandsen, J.]]
[[Category: Brandsen, J.]]
[[Category: Gros, P.]]
[[Category: Gros, P.]]
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[[Category: nuclear protein]]
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[[Category: Nuclear protein]]
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[[Category: ssdna binding]]
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[[Category: Ssdna binding]]
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[[Category: transcription]]
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[[Category: Transcription]]
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[[Category: transcriptional co-activator]]
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[[Category: Transcriptional co-activator]]
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[[Category: transcriptional cofactor]]
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[[Category: Transcriptional cofactor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:56:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:57:49 2008''
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Revision as of 01:56, 3 May 2008

Image:1pcf.gif

Template:STRUCTURE 1pcf

HUMAN TRANSCRIPTIONAL COACTIVATOR PC4 C-TERMINAL DOMAIN


Overview

The crystal structure of human replication and transcription cofactor PC4CTD reveals a dimer with two single-stranded (ss)DNA binding channels running in opposite directions to each other. This arrangement suggests a role in establishment or maintenance of melted DNA at promoters or origins of replication.

About this Structure

1PCF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site., Brandsen J, Werten S, van der Vliet PC, Meisterernst M, Kroon J, Gros P, Nat Struct Biol. 1997 Nov;4(11):900-3. PMID:9360603 Page seeded by OCA on Sat May 3 04:56:01 2008

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OCA

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