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2nmb

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Current revision (00:08, 28 December 2023) (edit) (undo)
 
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==DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES.==
==DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES.==
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<StructureSection load='2nmb' size='340' side='right'caption='[[2nmb]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''>
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<StructureSection load='2nmb' size='340' side='right'caption='[[2nmb]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2nmb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NMB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2nmb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NMB FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NUMB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nmb OCA], [https://pdbe.org/2nmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nmb RCSB], [https://www.ebi.ac.uk/pdbsum/2nmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nmb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nmb OCA], [https://pdbe.org/2nmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nmb RCSB], [https://www.ebi.ac.uk/pdbsum/2nmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nmb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/NUMB_DROME NUMB_DROME]] Required in determination of cell fate during sensory organ formation in embryos. Functions in nuclei and seems to interact with nucleic acids.<ref>PMID:2752427</ref>
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[https://www.uniprot.org/uniprot/NUMB_DROME NUMB_DROME] Required in determination of cell fate during sensory organ formation in embryos. Functions in nuclei and seems to interact with nucleic acids.<ref>PMID:2752427</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drome]]
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[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Forman-Kay, J D]]
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[[Category: Forman-Kay JD]]
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[[Category: Li, S C]]
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[[Category: Li S-C]]
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[[Category: McGlade, C J]]
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[[Category: McGlade CJ]]
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[[Category: Pawson, T]]
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[[Category: Pawson T]]
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[[Category: Vincent, S J.F]]
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[[Category: Vincent SJF]]
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[[Category: Zwahlen, C]]
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[[Category: Zwahlen C]]
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[[Category: Asymetr ic cell division]]
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[[Category: Cell cycle-gene regulation complex]]
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[[Category: Complex]]
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[[Category: Signal transduction]]
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Current revision

DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES.

PDB ID 2nmb

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