2o5a

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<StructureSection load='2o5a' size='340' side='right'caption='[[2o5a]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2o5a' size='340' side='right'caption='[[2o5a]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2o5a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_alcalophilus_subsp._halodurans"_boyer_et_al._1973 "bacillus alcalophilus subsp. halodurans" boyer et al. 1973]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O5A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2o5a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O5A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BH1328 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=86665 "Bacillus alcalophilus subsp. halodurans" Boyer et al. 1973])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o5a OCA], [https://pdbe.org/2o5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o5a RCSB], [https://www.ebi.ac.uk/pdbsum/2o5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o5a ProSAT], [https://www.topsan.org/Proteins/NESGC/2o5a TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o5a OCA], [https://pdbe.org/2o5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o5a RCSB], [https://www.ebi.ac.uk/pdbsum/2o5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o5a ProSAT], [https://www.topsan.org/Proteins/NESGC/2o5a TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/IOJAP_BACHD IOJAP_BACHD]] Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.[HAMAP-Rule:MF_01477]
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[https://www.uniprot.org/uniprot/IOJAP_HALH5 IOJAP_HALH5] Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.[HAMAP-Rule:MF_01477]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus alcalophilus subsp. halodurans boyer et al. 1973]]
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[[Category: Alkalihalobacillus halodurans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Acton, T B]]
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[[Category: Acton TB]]
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[[Category: Baran, M C]]
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[[Category: Baran MC]]
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[[Category: Benach, J]]
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[[Category: Benach J]]
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[[Category: Cunningham, K]]
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[[Category: Cunningham K]]
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[[Category: Ho, C H]]
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[[Category: Ho CH]]
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[[Category: Hunt, J F]]
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[[Category: Hunt JF]]
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[[Category: Janjua, H]]
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[[Category: Janjua H]]
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[[Category: Liu, J]]
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[[Category: Liu J]]
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[[Category: Ma, L C]]
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[[Category: Ma L-C]]
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[[Category: Montelione, G T]]
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[[Category: Montelione GT]]
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[[Category: Structural genomic]]
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[[Category: Rost B]]
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[[Category: Rost, B]]
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[[Category: Seetharaman J]]
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[[Category: Seetharaman, J]]
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[[Category: Su M]]
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[[Category: Su, M]]
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[[Category: Tong L]]
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[[Category: Tong, L]]
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[[Category: Xiao R]]
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[[Category: Xiao, R]]
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[[Category: Bhr21]]
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[[Category: Nesg]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Unknown function]]
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Revision as of 00:14, 28 December 2023

Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21

PDB ID 2o5a

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