3exa

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<StructureSection load='3exa' size='340' side='right'caption='[[3exa]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3exa' size='340' side='right'caption='[[3exa]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3exa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_alcalophilus_subsp._halodurans"_boyer_et_al._1973 "bacillus alcalophilus subsp. halodurans" boyer et al. 1973]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3exa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans Alkalihalobacillus halodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXA FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2qgn|2qgn]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BH2366, miaA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=86665 "Bacillus alcalophilus subsp. halodurans" Boyer et al. 1973])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/tRNA_dimethylallyltransferase tRNA dimethylallyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.75 2.5.1.75] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3exa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3exa OCA], [https://pdbe.org/3exa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3exa RCSB], [https://www.ebi.ac.uk/pdbsum/3exa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3exa ProSAT], [https://www.topsan.org/Proteins/NESGC/3exa TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3exa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3exa OCA], [https://pdbe.org/3exa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3exa RCSB], [https://www.ebi.ac.uk/pdbsum/3exa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3exa ProSAT], [https://www.topsan.org/Proteins/NESGC/3exa TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MIAA_BACHD MIAA_BACHD]] Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
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[https://www.uniprot.org/uniprot/MIAA_HALH5 MIAA_HALH5] Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus alcalophilus subsp. halodurans boyer et al. 1973]]
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[[Category: Alkalihalobacillus halodurans]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: TRNA dimethylallyltransferase]]
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[[Category: Abashidze M]]
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[[Category: Abashidze, M]]
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[[Category: Acton TB]]
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[[Category: Acton, T B]]
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[[Category: Baran MC]]
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[[Category: Baran, M C]]
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[[Category: Cunningham K]]
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[[Category: Cunningham, K]]
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[[Category: Forouhar F]]
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[[Category: Forouhar, F]]
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[[Category: Hunt JF]]
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[[Category: Hunt, J F]]
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[[Category: Janjua H]]
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[[Category: Janjua, H]]
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[[Category: Liu J]]
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[[Category: Liu, J]]
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[[Category: Ma L-C]]
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[[Category: Ma, L C]]
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[[Category: Montelione GT]]
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[[Category: Montelione, G T]]
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[[Category: Neely H]]
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[[Category: Structural genomic]]
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[[Category: Rost B]]
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[[Category: Neely, H]]
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[[Category: Seetharaman J]]
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[[Category: Rost, B]]
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[[Category: Shastry R]]
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[[Category: Seetharaman, J]]
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[[Category: Tong L]]
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[[Category: Shastry, R]]
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[[Category: Xiao R]]
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[[Category: Tong, L]]
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[[Category: Xiao, R]]
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[[Category: Alpha-beta protein]]
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[[Category: Atp-binding]]
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[[Category: Nesg]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transferase]]
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[[Category: Trna processing]]
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Revision as of 00:25, 28 December 2023

Crystal structure of the full-length tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.

PDB ID 3exa

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