3ezy
From Proteopedia
(Difference between revisions)
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==Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima== | ==Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima== | ||
| - | <StructureSection load='3ezy' size='340' side='right'caption='[[3ezy]]' scene=''> | + | <StructureSection load='3ezy' size='340' side='right'caption='[[3ezy]], [[Resolution|resolution]] 2.04Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EZY FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[3ezy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EZY FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ezy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezy OCA], [https://pdbe.org/3ezy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ezy RCSB], [https://www.ebi.ac.uk/pdbsum/3ezy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ezy ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3ezy TOPSAN]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ezy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ezy OCA], [https://pdbe.org/3ezy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ezy RCSB], [https://www.ebi.ac.uk/pdbsum/3ezy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ezy ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3ezy TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IOLG_THEMA IOLG_THEMA] Catalyzes the NAD(+)-dependent oxidation of myo-inositol (MI) to 2-keto-myo-inositol (scyllo-inosose), and thus probably functions in a myo-inositol degradation pathway together with IolM, IolN and IolO. Has no activity with scyllo-inositol and much reduced activity (78-fold lower catalytic efficiency) with 1D-chiro-inositol.<ref>PMID:23441918</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ezy ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ezy ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Thermotoga maritima]] | ||
[[Category: Almo SC]] | [[Category: Almo SC]] | ||
[[Category: Burley SK]] | [[Category: Burley SK]] | ||
Current revision
Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima
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Categories: Large Structures | Thermotoga maritima | Almo SC | Burley SK | Chang S | Freeman J | Gheyi T | Maletic M | Ramagopal UA | Toro R
