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3nqw

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Current revision (00:33, 28 December 2023) (edit) (undo)
 
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==A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses==
==A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses==
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<StructureSection load='3nqw' size='340' side='right' caption='[[3nqw]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='3nqw' size='340' side='right'caption='[[3nqw]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nqw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NQW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nqw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NQW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CG11900, Dmel_CG11900 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqw OCA], [http://pdbe.org/3nqw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nqw RCSB], [http://www.ebi.ac.uk/pdbsum/3nqw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nqw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqw OCA], [https://pdbe.org/3nqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nqw RCSB], [https://www.ebi.ac.uk/pdbsum/3nqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nqw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MESH1_DROME MESH1_DROME]] ppGpp hydrolyzing enzyme involved in starvation response.
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[https://www.uniprot.org/uniprot/MESH1_DROME MESH1_DROME] ppGpp hydrolyzing enzyme involved in starvation response.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/3nqw_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/3nqw_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drome]]
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[[Category: Drosophila melanogaster]]
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[[Category: Chung, J]]
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[[Category: Large Structures]]
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[[Category: Jeon, Y H]]
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[[Category: Chung J]]
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[[Category: Kim, H Y]]
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[[Category: Jeon YH]]
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[[Category: Kim, K J]]
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[[Category: Kim HY]]
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[[Category: Sun, D W]]
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[[Category: Kim KJ]]
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[[Category: Hydrolase]]
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[[Category: Sun DW]]
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[[Category: Ppgpp hydrolase]]
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[[Category: Pyrophosphohydrolase]]
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[[Category: Stringent response]]
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Current revision

A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses

PDB ID 3nqw

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