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3pva

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Current revision (00:34, 28 December 2023) (edit) (undo)
 
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==PENICILLIN V ACYLASE FROM B. SPHAERICUS==
==PENICILLIN V ACYLASE FROM B. SPHAERICUS==
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<StructureSection load='3pva' size='340' side='right' caption='[[3pva]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='3pva' size='340' side='right'caption='[[3pva]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pva]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PVA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pva]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PVA FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pva OCA], [http://pdbe.org/3pva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pva RCSB], [http://www.ebi.ac.uk/pdbsum/3pva PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pva ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pva OCA], [https://pdbe.org/3pva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pva RCSB], [https://www.ebi.ac.uk/pdbsum/3pva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pva ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
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[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Lysinibacillus sphaericus]]
[[Category: Lysinibacillus sphaericus]]
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[[Category: Penicillin amidase]]
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[[Category: Brannigan JA]]
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[[Category: Brannigan, J A]]
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[[Category: Dauter Z]]
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[[Category: Dauter, Z]]
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[[Category: Dodson EJ]]
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[[Category: Dodson, E J]]
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[[Category: Dodson GG]]
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[[Category: Dodson, G G]]
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[[Category: Mcvey CE]]
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[[Category: Mcvey, C E]]
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[[Category: Pundle AV]]
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[[Category: Pundle, A V]]
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[[Category: Rao KN]]
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[[Category: Rao, K N]]
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[[Category: Sivaraman H]]
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[[Category: Sivaraman, H]]
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[[Category: Suresh CG]]
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[[Category: Suresh, C G]]
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[[Category: Verma CS]]
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[[Category: Verma, C S]]
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[[Category: Amidohydrolase]]
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[[Category: Hydrolase]]
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[[Category: Ntn hydrolase]]
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[[Category: Penicillin v acylase]]
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Current revision

PENICILLIN V ACYLASE FROM B. SPHAERICUS

PDB ID 3pva

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