6zqr
From Proteopedia
(Difference between revisions)
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==Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with GlcNAc ligand bound== | ==Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with GlcNAc ligand bound== | ||
| - | <StructureSection load='6zqr' size='340' side='right'caption='[[6zqr]]' scene=''> | + | <StructureSection load='6zqr' size='340' side='right'caption='[[6zqr]], [[Resolution|resolution]] 1.93Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZQR FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6zqr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZQR FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zqr OCA], [https://pdbe.org/6zqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zqr RCSB], [https://www.ebi.ac.uk/pdbsum/6zqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zqr ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zqr OCA], [https://pdbe.org/6zqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zqr RCSB], [https://www.ebi.ac.uk/pdbsum/6zqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zqr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FBCD1_HUMAN FBCD1_HUMAN] Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components.<ref>PMID:19710473</ref> <ref>PMID:19892701</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Greenhough TJ]] | [[Category: Greenhough TJ]] | ||
[[Category: Shrive AK]] | [[Category: Shrive AK]] | ||
[[Category: Williams HM]] | [[Category: Williams HM]] | ||
Revision as of 00:56, 28 December 2023
Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with GlcNAc ligand bound
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