3hhk

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<StructureSection load='3hhk' size='340' side='right'caption='[[3hhk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3hhk' size='340' side='right'caption='[[3hhk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hhk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HHK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hhk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_subtype_1b Hepatitis C virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HHK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=77Z:2-({(3R)-3-[(3S)-1-(3-METHYLBUTYL)-2,4-DIOXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-1,1-DIOXIDO-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZIN-7-YL}OXY)ACETAMIDE'>77Z</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=77Z:2-({(3R)-3-[(3S)-1-(3-METHYLBUTYL)-2,4-DIOXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-1,1-DIOXIDO-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZIN-7-YL}OXY)ACETAMIDE'>77Z</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hhk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhk OCA], [https://pdbe.org/3hhk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hhk RCSB], [https://www.ebi.ac.uk/pdbsum/3hhk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hhk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hhk OCA], [https://pdbe.org/3hhk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hhk RCSB], [https://www.ebi.ac.uk/pdbsum/3hhk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hhk ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q99AU2_9HEPC Q99AU2_9HEPC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hepatitis c virus subtype 1b]]
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[[Category: Hepatitis C virus subtype 1b]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Concha, N O]]
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[[Category: Concha NO]]
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[[Category: Singh, O]]
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[[Category: Singh O]]
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[[Category: Atp-binding]]
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[[Category: Envelope protein]]
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[[Category: Hcv]]
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[[Category: Helicase]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Inhhibitor]]
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[[Category: Membrane]]
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[[Category: Ns5b]]
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[[Category: Nucleotide-binding]]
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[[Category: Polymerase]]
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[[Category: Rna replication]]
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[[Category: Transmembrane]]
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Revision as of 01:19, 28 December 2023

HCV NS5b polymerase complex with a substituted benzothiadizine

PDB ID 3hhk

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