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1pfq

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[[Image:1pfq.gif|left|200px]]
[[Image:1pfq.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1pfq |SIZE=350|CAPTION= <scene name='initialview01'>1pfq</scene>, resolution 1.90&Aring;
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The line below this paragraph, containing "STRUCTURE_1pfq", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= DPP4 OR ADCP2 OR CD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_1pfq| PDB=1pfq | SCENE= }}
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|RELATEDENTRY=[[1orw|1ORW]], [[1orv|1ORV]], [[1n1m|1N1M]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pfq OCA], [http://www.ebi.ac.uk/pdbsum/1pfq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1pfq RCSB]</span>
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}}
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'''crystal structure of human apo dipeptidyl peptidase IV / CD26'''
'''crystal structure of human apo dipeptidyl peptidase IV / CD26'''
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[[Category: Pierau, S.]]
[[Category: Pierau, S.]]
[[Category: Sweeney, A Mac.]]
[[Category: Sweeney, A Mac.]]
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[[Category: mch_1]]
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[[Category: Mch_1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:02:02 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:59:01 2008''
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Revision as of 02:02, 3 May 2008

Image:1pfq.gif

Template:STRUCTURE 1pfq

crystal structure of human apo dipeptidyl peptidase IV / CD26


Overview

Dipeptidyl peptidase IV is a multifunctional type II transmembrane serine protease glycoprotein. The high-resolution crystal structure of the homodimeric human apo dipeptidyl peptidase IV has been determined at 1.9 A resolution. In addition, the structure of the binary complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrol idine has been solved, revealing the nature of the covalent interaction with the active-site serine.

About this Structure

1PFQ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

High-resolution structure of human apo dipeptidyl peptidase IV/CD26 and its complex with 1-[([2-[(5-iodopyridin-2-yl)amino]-ethyl]amino)-acetyl]-2-cyano-(S)-pyrrol idine., Oefner C, D'Arcy A, Mac Sweeney A, Pierau S, Gardiner R, Dale GE, Acta Crystallogr D Biol Crystallogr. 2003 Jul;59(Pt 7):1206-12. Epub 2003, Jun 27. PMID:12832764 Page seeded by OCA on Sat May 3 05:02:02 2008

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