8ipk
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | The | + | ==The structure of human mitochondrial methyltransferase METTL15 with SAM== |
| - | + | <StructureSection load='8ipk' size='340' side='right'caption='[[8ipk]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ipk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IPK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ipk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ipk OCA], [https://pdbe.org/8ipk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ipk RCSB], [https://www.ebi.ac.uk/pdbsum/8ipk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ipk ProSAT]</span></td></tr> |
| - | [[Category: Lv | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MET15_HUMAN MET15_HUMAN] N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA (PubMed:31665743, PubMed:32371392). Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits (PubMed:31665743, PubMed:32371392).<ref>PMID:31665743</ref> <ref>PMID:32371392</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lv MQ]] | ||
| + | [[Category: Zhou WW]] | ||
Current revision
The structure of human mitochondrial methyltransferase METTL15 with SAM
| |||||||||||
