8iya

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'''Unreleased structure'''
 
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The entry 8iya is ON HOLD until 2025-04-04
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==Complex of SETDB1-derived peptide bound to UBE2E1==
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<StructureSection load='8iya' size='340' side='right'caption='[[8iya]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
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Authors: Du, Y.X., Liu, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8iya]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IYA FirstGlance]. <br>
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Description: Complex of SETDB1-derived peptide bound to UBE2E1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.43&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Liu, L]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8iya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8iya OCA], [https://pdbe.org/8iya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8iya RCSB], [https://www.ebi.ac.uk/pdbsum/8iya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8iya ProSAT]</span></td></tr>
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[[Category: Du, Y.X]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/UB2E1_HUMAN UB2E1_HUMAN] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.<ref>PMID:16428300</ref> <ref>PMID:20061386</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Du YX]]
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[[Category: Liu L]]

Revision as of 11:02, 3 January 2024

Complex of SETDB1-derived peptide bound to UBE2E1

PDB ID 8iya

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